What is the normal ratio of albumin to globulin?
In general, an albumin/globulin ratio between 1.1 and 2.5 is considered normal, although this can vary depending on the laboratory performing the test [4]. Your blood usually contains a little more albumin than globulin, which is why a normal ratio is slightly higher than 1 [1].
Is globulin bigger than albumin?
The globulins are a family of globular proteins that have higher molecular weights than albumins and are insoluble in pure water but dissolve in dilute salt solutions. Some globulins are produced in the liver, while others are made by the immune system. Globulins, albumins, and fibrinogen are the major blood proteins.
What is the normal range for globulin?
Normal value ranges are: Serum globulin: 2.0 to 3.5 grams per deciliter (g/dL) or 20 to 35 grams per liter (g/L) IgM component: 75 to 300 milligrams per deciliter (mg/dL) or 750 to 3,000 milligrams per liter (mg/L)
Why would albumin globulin be high?
High globulin levels may be a sign of: Certain types of blood cancers, such as multiple myeloma, Hodgkin disease, or leukemia. Hemolytic anemia. An autoimmune disease, such as lupus or rheumatoid arthritis. Tuberculosis.
What is a high globulin level?
High levels may indicate infection, inflammatory disease or immune disorders. High globulin levels may also indicate certain types of cancer, such as multiple myeloma, Hodgkin’s disease, or malignant lymphoma. However, abnormal results may be due to certain medications, dehydration, or other factors.
What is the difference between albumin and globulin?
The main difference between albumin and globulin is that albumin is the key protein in the blood, which regulates the osmotic pressure of blood whereas globulin is the second abundant type of proteins in the blood and is important in liver function, blood clotting, and fighting infections.
What happen if globulin is high?
What is a high globulin number?
Low globulin levels can be a sign of liver or kidney disease. High levels may indicate infection, inflammatory disease or immune disorders. High globulin levels may also indicate certain types of cancer, such as multiple myeloma, Hodgkin’s disease, or malignant lymphoma.
What is albumin level?
A normal albumin range is 3.4 to 5.4 g/dL. If you have a lower albumin level, you may have malnutrition. It can also mean that you have liver disease or an inflammatory disease. Higher albumin levels may be caused by acute infections, burns, and stress from surgery or a heart attack.