What is binder phenotype?

What is binder phenotype?

Binder phenotype, or maxillonasal dysostosis, is a distinctive pattern of facial development characterized by a short nose with a flat nasal bridge, an acute nasolabial angle, a short columella, a convex upper lip, and class III malocclusion.

What causes Binder syndrome?

Researchers have identified several environmental factors that may be associated with Binder type nasomaxillary dysplasia including birth trauma, vitamin K deficiency, or exposure of a developing infant to an anti-seizure drug known as Phenytoin or to an anti-blood clotting (anticoagulant) drug known as warfarin.

What is Bender’s syndrome?

Binder syndrome is a rare congenital disease affecting the face. Also called nasomaxillary hypoplasia or maxilla-facial dysplasia, the condition results in undergrowth of the central face and may include elements of the nose and upper jaw.

How common is Binder syndrome?

Binder syndrome also known as Binder type maxillonasal hypoplasia, is a rare congenital condition characterized by hypoplasia, or underdevelopment, of the central portion of the face. Binder syndrome is thought to be a rare disorder, occurring in approximately 1:10,000 live births.

What is Chondrodysplasia Punctata?

Chondrodysplasia punctata is an abnormality that appears on x-rays as spots (stippling) near the ends of bones and in cartilage. In most infants with X-linked chondrodysplasia punctata 1, this stippling is seen in bones of the ankles, toes, and fingers; however, it can also appear in other bones.

What is another word for binder?

What is another word for binder?

file folder
looseleaf folder ring binder
portfolio dossier
envelope wallet
sleeve case

What is a low nasal bridge?

A low nasal bridge is the flattening of the top part of the nose. The physical landmarks of the human face are very similar from one face to another. A low or absent nasal bridge can occur in association with infectious diseases or genetic diseases.

What is Nasomaxillary hypoplasia?

Nasomaxillary hypoplasia or Binder’s syndrome is a congenital deformity involving the midfacial skeleton characterised by underdevelopment of the nose and upper jaw, which is also called dish-face deformity.

What causes Midfacial hypoplasia?

Midfacial hypoplasia can be a feature of a number of congenital syndromic anomalies: Antley-Bixler syndrome. chromosome 1p36 deletion syndrome. chromosome 18q deletion syndrome.

What is Conradi Hünermann syndrome?

Conradi-Hünermann syndrome is a rare genetic disorder that affects approximately 1:100,000 to 1:200,000 births. This syndrome typically presents with skeletal abnormalities, short stature, differences in the form of the skull bones (craniofacial), eye or vision differences, and skin, hair, and nail abnormalities.

Can kids with RCDP talk?

She can walk, talk and play, despite misshapen bones, painful muscles and joints and deteriorating vision. In comparison, most children with RCDP never learn to sit, walk, talk or feed themselves.

What a binder means?

1 : a person or machine that binds something (such as books) 2a : something used in binding. b : a usually detachable cover (as for holding sheets of paper) 3 : something (such as tar or cement) that produces or promotes cohesion in loosely assembled substances.