What is Bextra valdecoxib used for?
Bextra (valdecoxib) is a nonsteroidal anti-inflammatory drugs (NSAID) that has been used to relieve the signs and symptoms of osteoarthritis and adult rheumatoid arthritis and for the treatment of primary dysmenorrhea. Bextra has been withdrawn from the U.S. market.
Is Bextra a sulfa drug?
The new boxed warning also states that Bextra contains sulfa, and patients with a history of allergic reactions to sulfa may be at a greater risk of skin reactions.
Why is valdecoxib banned?
Cox-2 category drugs such as Rofecoxib and Valdecoxib had become popular because unlike older non-steroidal anti inflammatory drugs like Ibuprofen, they did not cause stomach problems. However, Valdecoxib was banned globally as there were not sufficient cardiovascular safety data on its long term use.
When was Bextra recalled?
Why was Bextra removed from the market? On April 7, 2005, the FDA requested that Pfizer withdraw Bextra® (valdecoxib) from the market (for further information, click here). Pfizer responded that it “respectfully disagrees with FDA’s position regarding the overall risk/benefit profile of Bextra.
When was Bextra put on the market?
It was approved by the United States Food and Drug Administration on November 20, 2001, to treat arthritis and menstrual cramps. and was available by prescription in tablet form until 2005 when the FDA requested that Pfizer withdraw Bextra from the American market.
What arthritis drug was taken off the market?
Vioxx was once a popular drug to treat arthritis. But manufacturer Merck & Co. pulled it from the market in 2004 amid safety concerns. Research linked the drug to thousands of fatal heart attacks.
What class of drug is Bextra?
Bextra is in a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Bextra works by reducing substances in the body that cause inflammation, pain, and fever. Bextra is used to reduce pain, inflammation, and stiffness caused by osteoarthritis and adult rheumatoid arthritis.
What is the difference between Bextra tablets 10 and 20 mg?
BEXTRA Tablets 10 mg are white, film-coated, and capsule-shaped, debossed “10” on one side with a four pointed star shape on the other, supplied as: BEXTRA Tablets 20 mg are white, film-coated, and capsule-shaped, debossed “20” on one side with a four pointed star shape on the other, supplied as:
What is basebextra used to treat?
Bextra is used to reduce pain, inflammation, and stiffness caused by osteoarthritis and adult rheumatoid arthritis.
What is the recommended dose of Bextra for primary dysmenorrhea?
The recommended dose of BEXTRA Tablets for treatment of primary dysmenorrhea is 20 mg twice daily, as needed. BEXTRA Tablets 10 mg are white, film-coated, and capsule-shaped, debossed “10” on one side with a four pointed star shape on the other, supplied as: