What is a lupoid dermatosis?

What is a lupoid dermatosis?

Lupoid Dermatosis, also known as Exfoliative Cutaneous Lupus Erythematosus is a monogenic (controlled by one gene) autosomal recessive disease that has been described in German Shorthaired Pointers and Vizslas. Clinical signs become apparent before one year of age.

Do German shorthaired pointers have skin allergies?

Pointers are genetically predisposed to a variety of skin problems, including the development of skin allergies. Pointers often manifest seasonal allergies as patches of itchy dry skin, and as breed are highly susceptible to atopic dermatitis, the 2nd most common skin allergy in dogs.

What is dog ECLE?

At less than a year of age, the dogs develop widespread scaling and alopecia with gradual depigmentation and erosions/ulcers; this has been termed ‘exfoliative cutaneous lupus erythematosus of German short haired Pointers’ (ECLE). The dogs have progressive lethargy and lameness as well as haematological abnormalities.

Why does my GSP have dandruff?

Parasites are a common cause for dry skin on dogs. Dry, flaky skin can be a sign of mange parasites such as the Demodex mite, canine scabies, and cheyletiellosis (also known as walking dandruff).

How do you treat Lupoid dermatosis?

The most common drug that is used for treating lupoid dermatosis is cephalexin, but the drug hydroxychloroquine has recently been found to be more effective. Adalimumab has also been effective in treating the disease. In addition, prednisone is given to decrease inflammation, and antibiotics to prevent infections.

Can dogs take hydroxychloroquine?

Three dogs received hydroxychloroquine (5-10 mg/kg once daily) for 8 weeks, 7 months, and 9 months, respectively, with no side effects. Hydroxychloroquine appeared to slow clinical progression in two dogs on extended treatment and normalized globulin levels in all three dogs while receiving the drug.

How do you test for Lupoid dermatosis?

The most effective way to diagnose lupoid dermatosis is skin scrapings and biopsies. These tests will likely reveal the detection of edema, hyperkeratosis, and degeneration of some skin cells.