What happens if you eat grapefruit while taking pravastatin?
Grapefruit contains a chemical that can interfere with your body’s ability to break down or metabolize certain statin medications. When statin takers eat large amounts of grapefruit, the level of statins in their blood can increase, raising the possibility of side effects.
What happens when you eat grapefruit with statins?
Some substances can interact with statins With some statins, drinking grapefruit juice, or eating grapefruit, is a bad idea. Grapefruit juice can cause that statin to stay in your body much longer, and the drug can build up. This can increase the risk of muscle breakdown, liver damage, and even kidney failure.
Can you take pravastatin while pregnant?
Pravastatin seems to be a very safe medicine. It’s unusual to have any side effects. Do not take pravastatin if you are pregnant, trying to get pregnant or breastfeeding. Take pravastatin even if you feel well, as you will still be getting the benefits.
How much grapefruit is safe with statins?
Do not drink grapefruit juice if you’re taking simvastatin. Grapefruit juice increases the level of simvastatin in your blood and makes side effects more likely. Atorvastatin interacts with grapefruit juice if you drink large quantities (more than 1.2 litres daily), but an occasional glass is thought to be safe.
What fruit can’t you eat with statins?
Grapefruit and statins: Eating grapefruit, either the fruit itself or as juice, can slow the body’s ability to metabolize statin cholesterol-lowering drugs, which include Lipitor, Crestor and Zocor.
Can I eat pineapple with statins?
The risk of a drug-nutrient interaction between pineapple juice and statins is minimal to none.
How long does it take for pravastatin to get out of your system?
by Drugs.com It takes about 77 hours (3 days) for atorvastatin to be out of your system. The elimination half life of atorvastatin is approximately 14 hours. This is the time it takes for your body to reduce plasma drug levels by half.
Do statins cause birth defects?
Dr. A study that reviewed data from thousands of women, approximately half of whom took statins during their first trimester of pregnancy, showed that babies were not at increased risk of birth defects due to statin use. However, patients who did take statins in the first trimester had a higher rate of miscarriages.
What pregnancy category is pravastatin?
US FDA pregnancy category X: Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential …
Does pravastatin make you gain weight?
Some people may experience weight gain or weight loss while taking Pravachol. Both of these side effects were reported in clinical trials of the drug. If you’re concerned about your weight while taking Pravachol, talk with your doctor.