What drugs should not be taken with amphotericin?

What drugs should not be taken with amphotericin?

Some products that may interact with this drug include: anti-cancer drugs (e.g., mechlorethamine, nitrogen mustard), azole antifungals (e.g., ketoconazole, itraconazole), cidofovir, digoxin, flucytosine, medications that affect the kidneys (including pentamidine, tacrolimus, aminoglycosides such as gentamicin), muscle …

What is amphotericin used for?

Amphotericin B is an antifungal medication that fights infections caused by fungus. Amphotericin B is used to treat serious, life-threatening fungal infections.

What type of antibiotic is amphotericin?

Amphotericin B injection is in a class of medications called antifungals. It works by slowing the growth of fungi that cause infection.

What is the difference between posaconazole and voriconazole?

Conclusion: Posaconazole and voriconazole have the same prophylactic effect against IFDs in high-risk neutropenic Chinese patients. However, the safety of posaconazole is superior to that of voriconazole, while in terms of cost-effectiveness, voriconazole has an advantage over posaconazole.

What is the most serious side effect of amphotericin?

The principal acute toxicity of AmB deoxycholate includes nausea, vomiting, rigors, fever, hypertension or hypotension, and hypoxia. Its principal chronic adverse effect is nephrotoxicity.

What is the major side effect of amphotericin B?

SIDE EFFECTS: Fever, shaking, chills, flushing, loss of appetite, dizziness, nausea, vomiting, headache, shortness of breath, or fast breathing may occur 1 to 3 hours after the infusion is started.

What are the side effects of voriconazole?

Side Effects

  • Black, tarry stools.
  • blistering, peeling, loosening of the skin.
  • chest pain.
  • diarrhea.
  • difficulty seeing at night.
  • increased sensitivity of the eyes to sunlight.
  • itching, rash.
  • red irritated eyes.

Is voriconazole the same as fluconazole?

Voriconazole is the newest agent in the armamentarium against fungal infections. It is a triazole antifungal with a structure related to that of fluconazole and a spectrum of activity comparable to that of itraconazole.

Why is voriconazole hazardous?

The most common adverse effects reported with clinical use of voriconazole include visual disturbances, elevations of liver function tests and skin rash. Voriconazole has been associated with photosensitivity skin reactions especially during long term therapy. at the highest dose used in the test.

What medications interact with voriconazole?

Most frequently checked interactions

  • Advair Diskus (fluticasone / salmeterol)
  • Bactrim (sulfamethoxazole / trimethoprim)
  • Benadryl (diphenhydramine)
  • CellCept (mycophenolate mofetil)
  • Eliquis (apixaban)
  • Lasix (furosemide)
  • Levaquin (levofloxacin)
  • Lexapro (escitalopram)

Which antifungal drug at high doses has an antiandrogen effect?

Abstract. Ketoconazole, an antifungal agent, inhibits in vitro C17-C20 lyase, an enzyme involved in androgen biosynthesis.