What class of drug is zuclopenthixol?

What class of drug is zuclopenthixol?

Zuclopenthixol is a typical antipsychotic neuroleptic drug of the thioxanthene class. It mainly acts by antagonism of D1 and D2 dopamine receptors.

How does zuclopenthixol acetate work?

Zuclopenthixol works by blocking a variety of receptors in the brain, particularly dopamine receptors. Dopamine is a natural compound called a neurotransmitter, and is involved in transmitting messages between brain cells.

What is zuclopenthixol dihydrochloride used for?

Oral zuclopenthixol dihydrochloride (Clopixol) is an anti‐psychotic treatment for people with psychotic symptoms, especially those with schizophrenia.

Is zuclopenthixol a phenothiazine?

The more potent phenothiazines, e.g. fluphenazine, have a piperazine group added to the molecule; zuclopenthixol is a thioxanthine with a piperazine substitution. Thioxanthines have been used in schizophrenia and the manic phase of manic depressive illness as they block D1 and D2 dopamine receptors.

Is zuclopenthixol atypical antipsychotic?

First generation ‘typical’ antipsychotics such as zuclopenthixol are an older class of antipsychotic than second generation ‘atypical’ antipsychotics.

Is clopixol the same as zuclopenthixol?

Zuclopenthixol is a first generation antipsychotic. It is also known by the trade name Clopixol, Clopixol Acuphase and Clopixol Concentrate.

What is zuclopenthixol acetate?

As zuclopenthixol acetate (Clopixol-Acuphase, Cisordinol-Acutard), it is a shorter-acting intramuscular injection used in the acute sedation of psychotic inpatients. The effect peaks at 48–72 hours providing 2–3 days of sedation.

How do you inject zuclopenthixol?

How should zuclopenthixol decanoate be taken? A small dose is injected to test how your body responds. You will then be given a regular intramuscular injection which is administered into the muscle in the thigh or bottom.

Is Flupentixol and Zuclopenthixol the same?

Zuclopenthixol is thought to be more sedating than the related flupentixol, though possibly less likely to induce extrapyramidal symptoms than other typical depots.

Is Zuclopenthixol FDA approved?

It is known that zuclopenthixol is metabolized by Cytochrome P450 2D6. Zuclopenthixol was approved for use in Canada in 2011, but is not approved for use in the United States.

Is Zuclopenthixol a typical or atypical antipsychotic?

Zuclopenthixol (brand names Cisordinol, Clopixol and others), also known as zuclopentixol, is a medication used to treat schizophrenia and other psychoses. It is classed, pharmacologically, as a typical antipsychotic.