What antibiotics cover Corynebacterium?
Many antibiotics are effective, including penicillin, erythromycin, clindamycin, rifampin, and tetracycline; erythromycin or penicillin is the treatment of choice and is usually given for 14 days.
What is Corynebacterium susceptible to?
The susceptibilities of 265 strains of Corynebacterium species and other non-spore-forming gram-positive bacilli to 18 antimicrobial agents were tested. Most strains were susceptible to vancomycin, doxycycline, and fusidic acid.
What is antibiotic susceptibility pattern?
The overall antimicrobial susceptibility pattern of Gram-negative bacteria shows that they have a high level of resistance (>80%) against ampicillin and amoxicillin and an intermediate level of resistance to tetracycline and co-trimoxazole.
Is Corynebacterium sensitive to Bactrim?
Usually susceptible to multiple other agents: Clarithromycin 500mg po q12h. Bactrim DS (TMP-SMX) 160/800mg po bid.
How do you treat Corynebacterium Minutissimum?
The treatment of choice is erythromycin 250 mg four times daily for 2 weeks. Topical clindamycin twice daily also can be used. For severe cases, a combination of oral erythromycin and topical antibiotics may be needed. Recurrence can be minimized by the use of an antibacterial soap.
Does ceftriaxone treat Corynebacterium?
Based on CLSI M45 breakpoint criteria for Corynebacterium, highest resistance rates were observed for ciprofloxacin (73.7%), followed by trimethoprim/sulfamethoxazole (71.6%), erythromycin (65.5%) and ceftriaxone (63.6%; Table 2). Analysis by sub-groups showed C. jeikeium and C.
What causes Corynebacterium Jeikeium?
Most cases were associated with immunosuppression, a medical device, or trauma. C. jeikeium is a nonmotile, gram-positive bacillus that can appear to be coccobacillary.
Does doxycycline cover Corynebacterium?
Most strains were susceptible to vancomycin, doxycycline, and fusidic acid. Corynebacterium jeikeium and Corynebacterium urealyticum were the most resistant organisms tested.
What is susceptibility testing?
Susceptibility tests determine a microbe’s vulnerability to antimicrobial drugs by exposing a standardized concentration of organism to specific concentrations of antimicrobial drugs. Susceptibility testing can be done for bacteria, fungi, and viruses.
When do you perform antimicrobial susceptibility testing?
Antimicrobial susceptibility is an appropriate test whenever a specimen is collected from a suspected infection site. In the face of active infection, this information, along with the Gram stain and culture, allow the physician to select an appropriate antimicrobial agent to treat an infection.
Does Cipro cover Corynebacterium?
Resistance to beta-lactams, clindamycin, erythromycin, azythromycin, ciprofloxacin and gentamicin was common among strains of Corynebacterium xerosis and Corynebacterium minutissimum.
Can Corynebacterium cause a UTI?
Corynebacterium urealyticum is a cause of urinary tract infection and encrusting cystitis or pyelitis.
How resistant are Corynebacterium species to antimicrobial agents?
The susceptibilities of 265 strains of Corynebacterium species and other non-spore-forming gram-positive bacilli to 18 antimicrobial agents were tested. Most strains were susceptible to vancomycin, doxycycline, and fusidic acid. Corynebacterium jeikeium and Corynebacterium urealyticum were the most resistant organisms tested.
How many different types of Corynebacterium are there?
Twenty Corynebacterium strains were isolated and identified as Corynebacterium striatum(n= 7), Corynebacterium amycolatum(n= 7), C. urealyticum(n= 3), Corynebacterium afermentans(n= 2), and Corynebacterium pseudodiphtheriticum(n= 1).
How are isolates tested for antibiotic susceptibility?
All isolates have been tested for antibiotic susceptibility by standardized disc diffusion method and minimal inhibitory concentration (MIC) tests. Seventeen isolates demonstrated multidrug resistance phenotypes.
What is Corynebacterium pseudodiphtheriticum?
Corynebacterium pseudodiphtheriticumis normally found in the oropharyngeal flora of the human respiratory tract. In immune-suppressed patients, infections associated with this species include exudative pharyngitis, bronchitis, bronchiolitis, necrotizing tracheitis, tracheobronchitis, pneumonia, and lung abscess [18,19].